What to do if you get an allergic reaction from the COVID-19 vaccine?

Author: Oceane Rippin  |  Last update: Saturday, November 20, 2021

COVID-19
Common question

What to do if you get an allergic reaction from the COVID-19 vaccine?

If you get a COVID-19 vaccine and you think you might be having a severe allergic reaction after leaving the vaccination provider site, seek immediate medical care by calling 911.

What is the most common allergic reaction to COVID-19 vaccine?

Learn about common side effects of COVID-19 vaccines and when to call a doctor. An immediate allergic reaction means a reaction within 4 hours of getting vaccinated, including symptoms such as hives, swelling, or wheezing (respiratory distress).

How soon does anaphylaxis happen after COVID-19 vaccine?

Symptoms of anaphylaxis often occur within 15-30 minutes of vaccination, though it can sometimes take several hours for symptoms to appear.

Is it normal if you react to the COVID-19 vaccine?

Minor side effects are a normal sign that the immune system is mounting a protective response following vaccination, although they aren't universal.

Is it normal to have side effects after second COVID-19 vaccine?

Side effects after your second shot may be more intense than the ones you experienced after your first shot. These side effects are normal signs that your body is building protection and should go away within a few days.

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How soon do side effects start after COVID-19 vaccine booster?

You probably experienced COVID-19 vaccine side effects fairly quickly when you had your initial injections. The same is true for COVID-19 vaccine booster shots: Most people notice side effects within the first 24 hours. The symptoms typically only last a day or two. Some people don’t notice any side effects.

How long do side effects last after the COVID-19 booster shot?

They're very similar to what happens after the second dose, which is that you do tend to get pain at the injection site, usually just lasts a few days, and usually it's not severe. And then you can get systemic side effects such as fever, fatigue, headache, and again, that usually goes away after a day or two.

What are the common side effects of the COVID-19 vaccine?

The most commonly reported side effects were pain at the injection site, tiredness, headache, muscle pain, chills, joint pain, and fever.

What is an immediate allergic reaction to the COVID-19 vaccine?

An immediate allergic reaction means a reaction within 4 hours of getting vaccinated, including symptoms such as hives, swelling, or wheezing (respiratory distress).

Is it normal that I feel tired after taking the COVID-19 vaccine?

For most people, the side effects of the COVID-19 vaccine are mild and don't last long—between a few hours and a few days at most. Some people experience a sore arm, or flu-like symptoms such as fatigue, fever, and chills.

What are the common side effects of the Pfizer-BioNTech COVID-19 vaccine?

The most commonly reported side effects were pain at the injection site, tiredness, headache, muscle pain, chills, joint pain, and fever. Side effects typically started within two days of vaccination and resolved 1-2 day later.

What are the common side effects of the Moderna and Pfizer COVID-19 booster shots?

The most common side effects reported after getting a third shot of an mRNA vaccine, the type made by Moderna and Pfizer, were pain at the injection site, fatigue, muscle pain, headache and fever, followed by chills and nausea.

What are the delayed localized hypersensitivity reactions of the Moderna COVID-19 vaccine?

The delayed localized cutaneous reactions developed in a median (range) of 7 (2-12) days after receiving the Moderna COVID-19 vaccine. These reactions occurred at or near the injection site and were described as pruritic, painful, and edematous pink plaques.

Who should not get the Moderna COVID-19 vaccine?

If you have had a severe allergic reaction (anaphylaxis) or an immediate allergic reaction, even if it was not severe, to any ingredient in an mRNA COVID-19 vaccine (such as polyethylene glycol), you should not get an mRNA COVID-19 vaccine.

What are the most common skin manifestations of COVID-19?

The clinical presentation appears varied, though in a study of 171 persons with laboratory-confirmed COVID-19 (ranging from mild to severe disease), the most common skin manifestations reported were: a maculopapular rash (22%), discolored lesions of the fingers and toes (18%), and hives (16%).

Should I get the 2nd mRNA COVID-19 vaccine if I had an allergic reaction?

• If you had a severe or immediate allergic reaction after getting the first dose of an mRNA COVID-19 vaccine, you should not get a second dose of either of the mRNA COVID-19 vaccines (Moderna or Pfizer-BioNTech).

Does COVID-19 have an effect on your skin?

Cutaneous illnesses due to SARS-CoV-2 have been rising worldwide. These diseases typically fall into five different patterns, which include maculopapular rash, vesicular rash, pseudo-chilblain, livedo or necrosis, and urticaria. A red rash and urticaria are considered to be the most common manifestations of COVID-19.

Are there any long term effects of COVID-19 vaccine?

Serious side effects that could cause a long-term health problem are extremely unlikely following any vaccination, including COVID-19 vaccination. Vaccine monitoring has historically shown that side effects generally happen within six weeks of receiving a vaccine dose.

How long do COVID-19 booster side effects last?

You probably experienced COVID-19 vaccine side effects fairly quickly when you had your initial injections. The same is true for COVID-19 vaccine booster shots: Most people notice side effects within the first 24 hours. The symptoms typically only last a day or two. Some people don't notice any side effects.

How long do side effects from Moderna's COVID-19 booster last?

A: They are very similar to what happens after the second dose, which is that you do tend to get pain at the injection site, usually just lasts a few days, and usually it's not severe. And then you can get systemic side effects such as fever, fatigue, headache, and again, that usually goes away after a day or two.

Is there a difference between a booster and COVID-19 vaccine?


Are booster shots the same formulation as existing vaccines? Yes. COVID-19 booster shots are the same formulation as the current COVID-19 vaccines. However, in the case of the Moderna COVID-19 vaccine booster shot, it is half the dose of the vaccine people get for their initial series.

Is it normal for the second Pfizer COVID-19 vaccine to cause arm pain?


As with all two-dose vaccines, those getting either Pfizer's or Moderna's COVID-19 vaccination are more likely to experience arm pain after the second dose. This side effect is also more common if you are under 65 years old.

Are you at risk of experiencing an autoimmune disease flare-up from COVID-19 vaccine?

There is a risk that flare-ups may occur. That being said, it has been observed that people living with autoimmune and inflammatory conditions are at higher risk of experiencing severe symptoms from a COVID-19 infection.

Is it normal for the Pfizer and Moderna vaccines to cause swelling in the armpit?

The swelling in the armpit was a recognized side effect in the large trials of the Moderna and Pfizer-BioNTech vaccines. According to The New York Times, in Moderna's study, "11.6% of patients reported swollen lymph nodes after the first dose, and 16% after the second dose.

Is it normal for my arm to hurt after my second shot of COVID-19?


A sore, red, or swollen arm is just one of several common side effects from vaccines. Other expected reactions include headache, a low-grade fever (temperature less than 100.4℉), tiredness, and muscle aches.

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